Nevadensin
APC-991
Nevadensin
Cat. No.
APC-991
CAS No.
10176-66-6
MF
C18H16O7
MW
344.3
Nevadensin is a natural flavonoid, is a selective human carboxylesterase 1 (hCE1) inhibitor, Nevadensin has a variety of pharmacological effects.
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Technical Data
Description
Storage and Shipping
References
Product Name
CAS No.
10176-66-6
MF
C18H16O7
MW
344.3
Specification
98%
Research Area
Anti-inflammatory, anti-tumour and anti-hypertensive
Description
Nevadensin is a natural flavonoid, is a selective human carboxylesterase 1 (hCE1) inhibitor, Nevadensin has a variety of pharmacological effects. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat.
References
[1]. Ya-Qiao Wang, et al. Nevadensin is a naturally occurring selective inhibitor of human carboxylesterase 1. Int J Biol Macromol. 2018 Dec;120(Pt B):1944-1954.
[2]. Suksamrarn A, et al. Antimycobacterial and antioxidant flavones from Limnophila geoffrayi. Arch Pharm Res. 2003 Oct;26(10):816-20.
[3]. Müller L, et al. Topoisomerase poisoning by the flavonoid nevadensin triggers DNA damage and apoptosis in human colon carcinoma HT29 cells. Arch Toxicol. 2021 Dec;95(12):3787-3802.
[4]. Shi H, et al. Activating the Hippo pathway by nevadensin overcomes Yap-drived resistance to sorafenib in hepatocellular carcinoma. Discov Oncol. 2023 May 27;14(1):83.
[5]. Zhang YF , et al. Nevadensin relieves food allergic responses and passive cutaneous anaphylaxis in mice through inhibiting the expression of c-Kit receptors. Food Funct. 2020 Dec 1;11(12):10375-10385.
Disclaimer
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